Arsenal know that they will reach the last 16 of the Champions League on Wednesday if they avoid a heavy defeat against Napoli in Italy.
The Gunners currently top Group F by three points, while Napoli sit behind second-placed Borussia Dortmund on goal difference.
However, Arsene Wenger's side will exit the competition if they are thrashed by the Italian outfit and Dortmund defeat Marseille.
Arsenal saw off Napoli 2-0 thanks to goals from Mesut Ozil and Olivier Giroud when the two teams met at the Emirates Stadium in October.
Marek Hamsik and Camilo Zuniga miss out for the hosts, while Alex Oxlade-Chamberlain, Bacary Sagna and Lukas Podolski all remain sidelined for the visitors.
Meanwhile, Jack Wilshere could be forced to sit out the game after picking up an ankle knock during Arsenal's recent 1-1 draw with Everton in the Premier League.
Recent form
Napoli: WLLLWD
Arsenal: LWWWWD
Possible starting lineups
Napoli: Rafael; Maggio, Fernandez, Albiol, Reveillere; Dzemaili, Pandev, Inler, Callejon, Insigne; Higuain
Arsenal: Szczesny; Jenkinson, Koscielny, Mertesacker, Gibbs; Walcott, Arteta, Ozil, Ramsey, Cazorla; Giroud
Sports Mole says: 0-2
