The former Real Madrid centre-back has struggled with a number of muscular injuries in recent weeks, with further tests expected to take place in the coming days.

However, according to Radio Kiss Kiss, the Spaniard will not be fit for the top-of-the-table encounter with Roma, who currently lead the way in Serie A with 21 points, two points ahead of Napoli.

Argentine forward Gonzalo Higuain, however, is expected to be fit to lead Napoli's line.

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Premier League Table

	Team	P	W	D	L	F	A	GD	PTS
1	Atalanta BC Atalanta	17	13	1	3	42	19	23	40
2	Napoli	17	12	2	3	26	12	14	38
3	Inter Milan	15	10	4	1	40	15	25	34
4	Lazio	17	11	1	5	32	24	8	34
5	Fiorentina	15	9	4	2	28	11	17	31
6	Juventus	17	7	10	0	28	13	15	31
7	Bologna	16	7	7	2	23	18	5	28
8	AC Milan	16	7	5	4	25	16	9	26
9	Udinese	16	6	2	8	19	25	-6	20
10	Roma	17	5	4	8	23	23	0	19
11	Empoli	17	4	7	6	16	19	-3	19
12	Torino	17	5	4	8	17	22	-5	19
13	Genoa	17	3	7	7	14	26	-12	16
14	Lecce	17	4	4	9	11	29	-18	16
15	Parma	17	3	6	8	23	33	-10	15
16	Como	16	3	6	7	18	28	-10	15
17	Hellas Verona Hellas Verona	17	5	0	12	21	40	-19	15
18	Cagliari Cagliari	17	3	5	9	16	28	-12	14
19	Venezia Venezia	17	3	4	10	17	30	-13	13
20	Monza	17	1	7	9	15	23	-8	10