Genoa vs. Cagliari (Sunday, 11.30am)
Aiming for a victory to start Patrick Vieira's tenure positively, Genoa seek maximum against a Cagliari side one place ahead of them in the Serie A table ahead of Sunday's gameweek 13 match at Stadio Comunale Luigi Ferraris.
The Frenchman replaced the sacked Alberto Gilardino during the international break and has been tasked to guide the Rossoblu away from relegation trouble.
We say: Genoa 1-1 Cagliari
It is unclear how Vieira's arrival at Genoa affects Sunday's outcome, especially given their winless home form. However, they should avoid losing to fellow strugglers Cagliari on the Frenchman's managerial bow in Italian football.
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Como vs. Fiorentina (Sunday, 2.00pm)
Having surged to within one point of the Serie A summit, Fiorentina will aim to pick up where they left off before the break when they visit Como on Sunday.
When international football intervened, the Viola had won six league games on the spin; meanwhile, their ailing hosts are without a win in six and sit just above the drop zone.
We say: Como 1-2 Fiorentina
While a two-week break may have disrupted Fiorentina's momentum, they will return to action against a Como side that simply cannot keep the back door shut.
The Lagunari have shipped 10 goals in four games since returning to Stadio Sinigaglia after development works delayed their first home fixture, and the Viola are well-equipped to punish them further.
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Torino vs. Monza (Sunday, 2.00pm)
Having entered the international break with a run of three straight defeats, both Torino and Monza will try to stop the rot on Sunday, when they lock horns in Turin.
Toro signed off with yet another loss to city rivals Juventus, while their visitors were beaten by Lazio and are stuck inside Serie A's drop zone.
We say: Torino 1-1 Monza
Monza have actually fared better on the road than at home this season, and they may take a point home from Turin, as their hosts have issues to fix at both ends of the pitch.
Torino's fast start to the 2024-25 campaign is long forgotten now, and the pressure to produce improved results may count against them when hosting lowly opponents.
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Napoli vs. Roma (Sunday, 5.00pm)
Returning to the Roma hotseat for a third spell in charge, Claudio Ranieri will lead the Giallorossi into Sunday's Serie A showdown with Napoli.
Having been lured out of retirement to rescue his beloved club, Ranieri now meets Antonio Conte's league leaders in this season's first Derby del Sole.
We say: Napoli 1-0 Roma
As Roma are in disarray, it might take Claudio Ranieri some time to turn things around; meanwhile, Napoli are already a well-oiled machine.
After letting the chasing pack close within striking distance of top spot, the Partenopei should be ready to go again, resuming normal service with another home win.
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Lazio vs. Bologna (Sunday, 7.45pm)
Two teams enjoying some superb form will meet at Stadio Olimpico on Sunday, as Lazio and Bologna both aim to extend winning streaks in Serie A.
Before the international break, Lazio surged up the standings with four straight successes, while their Rossoblu rivals finally started turning draws into wins.
We say: Lazio 2-1 Bologna
Averaging over two goals per game this season, Lazio are sure to put Bologna's back line through a thorough test, as they are spoiled for in-form options.
The Rossoblu have proved difficult to beat in Serie A, but their undefeated streak may finally be ended by such free-scoring opponents.
