Steve Bruce admitted upon his appointment as Newcastle boss at the start of the season that he wanted to be the man to kickstart the club's love affair with cup competitions.
The 59-year-old has not exactly managed to do that just yet, with the Magpies exiting the EFL Cup on penalties to Leicester City in the third round, before stuttering past Rochdale in their opening FA Cup tie.
Forty-year-old substitute Aaron Wilbraham scored late on to cancel out Miguel Almiron's fierce first-half strike at Spotland, but Bruce's men made no mistake in the replay as they ran out 4-1 winners on home soil last week.
A home match against another third-tier side in Oxford has supporters dreaming of making it into the latter stages of the competition.
Given their Premier League position - seven points above the dropzone with 14 games to go - Bruce is expected to field a strong side on Saturday.
Newcastle fans will not need reminding that nothing is certain in the FA Cup, though, having been knocked out by Oxford at this very stage three seasons ago.
That was only the sixth time in their history they had made it to the fifth round, where they were beaten 3-2 by Middlesbrough.
Karl Robinson must now decide whether to go with a strong side for the visit to St James' Park or instead prioritise his side's promotion push, knowing there is a big trip to Peterborough United up next.
As for Bruce, he will be eager for his players to continue building some moment on the back of their dramatic late 2-2 draw at Everton that extended their unbeaten run to five games in all competitions.
Newcastle United's FA Cup form: DW
Newcastle United's form (all competitions): LDDWWD
Oxford United's FA Cup form: WWW
Oxford United's form (all competitions): WLWLDD
Newcastle's players have been dropping like flies over the past month so Bruce will be wary of pushing first-team regulars too hard.
Oxford made the decision to travel up to Newcastle a day early as a chance to "take stock", in the words of boss Robinson.
There is no doubt that promotion to the Championship is the top target for the U's this season, but a fourth-round FA Cup tie away at an established Premier League club will surely tempt Robinson into fielding close to his strongest-possible XI.
That could mean a start up top for Tariqe Fosu, who has eight goals in 25 League One appearances this campaign.
Newcastle United possible starting lineup:
Darlow; Lejeune, Lascelles, Schar; Ritchie, Longstaff, Shelvey, Allan; Saint-Maximin, Joelinton, Almiron
Oxford United possible starting lineup:
Eastwood; Long, Dickie, Mousinho, Ruffels; Sykes, Rodriguez, Baptiste; Holland, Mackie, Fosu-Henry
We say: Newcastle United 2-0 Oxford United
Oxford have collected two points from a possible 12 in 2020. That disappointing run of form, combined with Newcastle's new-found resilience, suggests a repeat of their 2017 upset against the same opponents will not be on the cards this weekend.