Meanwhile, the Magpies play host to the Eagles having lost out to Burnley last weekend, which represented their first defeat in four outings.
Prior to the setback at Turf Moor, two wins and a draw had been recorded from three matches, helping the Magpies remain seven points clear of the relegation zone.
Bruce will no doubt be looking ahead rather than backwards, but putting distance between themselves and the bottom three was the priority when he replaced Rafael Benitez during the summer.
However, Bruce will see that Newcastle now have a tough run of fixtures, and an extended period with a low return would change the mood at St James' Park.
As it stands, though, Newcastle have recorded just one point fewer than their next opponents, creating the opportunity to move into the top half of the table by Saturday night.
Palace manager Roy Hodgson would have probably hoped to see his team placed even higher given their overall form, but a return of eight points and three clean sheets from four matches will delight the veteran.
In sharp contrast to Newcastle, Palace now have a run of games which they will feel are winnable and have the potential to catapult the club into contention for a Champions League spot.
While Hodgson will call for focus against teams occupying places in the bottom half, there is enough breathing space ahead of the dropzone where Palace can throw caution to the wind.
Just five goals have come from their last seven outings, however, and that will need to improve if the London outfit are to make an impact further up the division.
Newcastle United Premier League form: WLDWWL
Crystal Palace Premier League form: LLWWDD
Jairo Riedewald was forced off at half time against Brighton, but Hodgson will hope that the Dutchman can recover from injury in time for the trip to St James' Park.
However, given the upcoming busy schedule, Bruce may be against taking any risks with either player from the opening whistle.
Newcastle United possible starting lineup:
Dubravka; Yedlin, Fernandez, Schar, Dummett, Willems; Atsu, Hayden, S.Longstaff, Joelinton; Carroll
Crystal Palace possible starting lineup:
Guaita; Kelly, Tomkins, Dann, Riedewald; Kouyate, Milivojevic, McArthur; Townsend, Ayew, Zaha
We say: Newcastle United 1-1 Crystal Palace
While this could be a game where defences are on top, we would be surprised if it remains goalless. Neither team are regulars on the scoresheet, but netting a goal apiece feels about right for this contest.
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