Kostas Mitroglou will be hoping to continue his rich vein of form as he starts up front for an Olympiacos side looking to beat Paris Saint-Germain to qualify for the Champions League knockout stages.
The visitors also have Costa Rican winger Joel Campbell, who joined the Athens club on loan from Arsenal, in attack to face PSG.
Uruguayan forward Edinson Cavani starts for the hosts alongside former Napoli teammate Ezequiel Lavezzi.
Swedish international striker Zlatan Ibrahimovic, who has scored seven goals in the group phase so far this season, will lead the line for Laurent Blanc's side.
Les Parisiens are currently on a run of 34 games without defeat in all competitions, but Olympiacos are also unbeaten since their loss in the return fixture back in September.
Paris Saint-Germain: Sirigu, Thiago Silva, Alex, Maxwell, Van der Wiel, Motta, Matuidi, Verratti, Cavani, Ibrahimovic, Lavezzi
Olympiacos: Roberto, Maniatis, Holebas, Manolas, Leandro Salino, Bong, Samaris, Fuster, Siovas, Campbell, Mitroglou