Keylor Navas has been preferred to Iker Casillas in goal as Real Madrid look to seal first place in Group B against Basel.
Alvaro Arbeloa starts at right-back for Los Blancos as Daniel Carvajal is left out the European champions' matchday squad.
Luka Modric misses the game in Switzerland with a thigh injury, but manager Carlo Ancelotti has picked an attacking lineup with Cristiano Ronaldo, Isco, Gareth Bale, Karim Benzema and James Rodriguez all featuring at St-Jakob Park.
Basel will face the group leaders with Marco Streller (back) and Granit Xhaka (thigh) missing from the starting lineup for Paulo Sousa's men.
The hosts will progress to the last 16 if they beat Real and Liverpool fail to beat Ludogorets Razgrad in Bulgaria.
Basel: Vaclik, Degen, Schar, Suchy, Safari, Elneny, Frei, Zuffi, Gonzalez, Embolo, Gashi
Real Madrid: Navas, Varane, Ramos, Coentrao, Ronaldo, Kroos, Benzema, Rodriguez, Bale, Arbeloa, Isco