Los Blancos were in Champions League action on Tuesday night, sharing the points with Paris Saint-Germain at the Bernabeu as the French champions recovered from two goals behind to pick up a 2-2 draw.
Here, Sports Mole looks at how the capital giants could line up when they take to the field in Spain's top flight.
There was a fear that Eden Hazard had picked up a potentially long-term injury during Tuesday's clash with PSG, but Madrid confirmed on Wednesday that the Belgium international had suffered just a bruised leg.
Hazard has not been officially ruled out of Saturday's contest, although it seems unlikely that Zidane will take a risk with the summer arrival.
Marco Asensio, James Rodriguez and Lucas Vazquez are also still on the sidelines, but Nacho has stepped up his recovery from a knee problem in recent days and could be involved this weekend.
Gareth Bale is also pushing for a start having been involved off the bench since returning from international duty, and Hazard's expected absence could open the door for the Wales international to feature.