The long-term futures of James Rodriguez and Isco at Real Madrid are reportedly uncertain.
According to Marca, senior officials at the Bernabeu have been less than impressed with the performances that the pair have put in this season.
As a result, the report adds, Los Blancos are now prepared to cash in on both players in the summer.
Colombia international Rodriguez has long been linked with Manchester United, while the likes of Arsenal, Chelsea and Manchester City have all been credited with an interest in playmaker Isco.
The duo were jeered off by Real supporters when they were substituted during the weekend's 1-0 defeat at home to rivals Atletico Madrid.