Olimpia vs. Flamengo (Wednesday, 11.15pm)
2019 Copa Libertadores champions Flamengo will travel to three-times winners Olimpia in the first leg of their quarter-final clash on Wednesday.
The Paraguayans have failed to win any of their last three home matches in all competitions, while the visitors have won each of their last four games on the road.
We say: Olimpia 1-2 Flamengo
Both sides have looked defensively vulnerable in recent weeks and so we could see a few goals scored on Wednesday evening.
The visitors will head into this game as the slight favourites and we can see them coming away with a narrow victory.
> Click here to read our full preview for this match
River Plate vs. Atletico Mineiro (Thursday, 1.30am)
River Plate and Atletico Mineiro will meet for the very first time when they face each other in the first leg of their Copa Libertadores quarter-final clash on Thursday.
The hosts have won just one of their last five home matches across all competitions, while the visitors have lost just one of their last six games on the road.
We say: River Plate 0-1 Atletico Mineiro
River Plate and Atletico Mineiro will be keen to ensure that they remain in the tie for the second leg, so both teams may take a cautious approach to Thursday's game.
A closely-fought contest is set to be played out in Buenos Aires, however we feel that the visitors will secure a narrow victory.