Union vs. San Lorenzo (Saturday, 8.00pm)
Union could go top in the Argentine Primera Division on Saturday when they welcome struggling San Lorenzo to Estadio 15 de Abril.
The hosts are one of four clubs on 10 points heading into the fifth round, and they aim to dispatch their fourth-bottom opponents keen to respond after a below-par start.
We say: Union 1-0 San Lorenzo
While San Lorenzo no longer having continental distractions means a resurgence could be imminent, the safer bet would be backing the hitherto undefeated Union to nick a marginal victory over the winless away side in Santa Fe.
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Huracan vs. Independiente Rivadavia (Saturday, 10.00pm)
Huracan and Independiente Rivadavia are separated by five places in the Argentine Primera Division table heading into Saturday's gameweek five encounter at the Tomas Adolfo Duco Stadium.
The hosts are one of four undefeated sides at the start of the season, but they could be leapfrogged by their opponents from Mendoza after round five's fixture.
We say: Huracan 1-0 Independiente Rivadavia
Saturday's outcome will depend on Huracan finding ways to penetrate Independiente Rivadavia's five-player defence. The hosts should be beneficiaries of Pussetto and Fertoli's admirable starts this term to secure their fourth win.
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Tucuman vs. Defensa (Sunday, 12.30am)
Seven places separate Atletico Tucuman and Defensa y Justicia in the Argentine Primera Division table heading into Saturday's round five encounter at Estadio Jose Fierro.
The home side are winless since the campaign's opening round, but their opponents are in worse shape, having not won in four gameweeks.
We say: Atletico Tucuman 1-1 Defensa y Justicia
Saturday's encounter is difficult to call because of both sides' underwhelming results preceding gameweek five. Tucuman are winless in four games in all competitions, while Defensa have not recorded victory of any kind since mid-April, thus pointing to a share of the spoils at the Jose Fierro.