Peterborough vs. Derby (Saturday, 12.30pm)
After suffering heavy defeats in their opening two matches of the new season, Peterborough United will be hoping to claim their first Championship win at home against a depleted Derby County side on Saturday lunchtime.
The two teams last faced each other in April 2013, with Nigel Clough's Rams securing a 3-1 league victory at Pride Park.
We say: Peterborough United 1-2 Derby County
Peterborough were one of just two Championship sides who failed to score on the opening day, but we fancy them to find the net this weekend.
Derby, meanwhile, are taking positive momentum into Saturday's game and even though they have a depleted squad, their starting lineup will be able to compete against the Posh.
A closely-fought contest is set to be played out at the Weston Homes Stadium, but we feel that the visitors could surprise many and secure a narrow victory.
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Barnsley vs. Coventry (Saturday, 3.00pm)
Barnsley welcome Coventry City to Oakwell on Saturday afternoon for their opening home fixture of the 2021-22 Championship season.
Both sides head into this game after suffering League Cup exits in the first round against lower league opposition.
We say: Barnsley 1-1 Coventry City
After their opening day victory Coventry will fancy their chances of securing another three points this weekend. However, the away team has won none of the last 13 league meetings between Barnsley and the Sky Blues, and we think that this run is set to continue.
Nevertheless, we are predicting a score draw between two evenly-matches sides, which should be considered a good result for the visitors.
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Birmingham vs. Stoke (Saturday, 3.00pm)
Both winners on the Championship's opening day, Birmingham City meet Stoke City at St Andrew's on Saturday, with the pair seeking to extend their successful starts to the campaign.
After adding Carabao Cup victory to league wins last weekend, the Midlands rivals will now go head-to-head for another three points.
We say: Birmingham City 1-2 Stoke City
Something must give after two wins from two for either side, and Stoke - whose clever signings and clearance of overpaid pros could transform their fortunes this term - are the most likely to continue their flawless run.
Though Lee Bowyer takes pride in his team's defensive solidity, the visitors possess enough individual quality to pick them off on a couple of occasions and take maximum points back to the Potteries.
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Blackpool vs. Cardiff (Saturday, 3.00pm)
Cardiff City will be looking to pick up from where they left off at the end of last season away from home when they make the trip to Blackpool on Saturday afternoon.
Both sides kicked off their 2021-22 Championship campaigns with 1-1 draws last weekend, with Cardiff being held by Barnsley and Blackpool snatching a late point at Bristol City.
We say: Blackpool 1-1 Cardiff City
Both sides will be eager to get their first league win on the board at the second time of asking this weekend.
Cardiff do not have the best of records at Bloomfield Road, where Blackpool are unbeaten in five, and we can see them coming away disappointed on this latest trip to the seaside.
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Huddersfield vs. Fulham (Saturday, 3.00pm)
Following opening-day draws, Huddersfield Town and relegated Fulham meet at the John Smith's Stadium on Saturday, both seeking a first win of the Championship season.
While the Terriers took a point home from Derby last weekend, amid testing circumstances, Marco Silva's side began life back in the second tier with a disappointing draw against Middlesbrough.
We say: Huddersfield Town 0-2 Fulham
Not only have Huddersfield seen their season already disrupted by infections, their form this calendar year makes them one of the candidates to be battling against the drop. In 2021, the Terriers have recorded just three league wins, and are not likely to add to that meagre tally on Saturday.
Fulham should dominate the ball, so must now focus on finding a more clinical edge - which their experienced forwards are more than capable of doing at this level.
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Hull City vs. QPR (Saturday, 3.00pm)
On a high from their impressive opening-day victory, Hull City will be looking to claim another win when they host Queens Park Rangers in the Championship on Saturday afternoon.
The Tigers are unbeaten in each of their last eight league games on home soil, while the visitors have won each of their last three league matches on the road.
We say: Hull City 2-2 Queens Park Rangers
Goals are to be expected on Saturday, as this fixture has seen three or more goals scored in each of the last seven meetings.
QPR will be eager to claim their first victory of the new season, but with little separating these two teams, we could see an entertaining encounter with both sides taking a share of the spoils.
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Middlesbrough vs. Bristol City (Saturday, 3.00pm)
Middlesbrough welcome Bristol City to the Riverside Stadium on Saturday afternoon looking to build on last weekend's draw at Fulham.
Despite recording the same result as their hosts, Bristol City are eager to respond to conceding a last-gasp equaliser to newly-promoted Blackpool.
We say: Middlesbrough 1-1 Bristol City
Having both recorded disappointing results in midweek, both Warnock and Pearson are aware that they can ill-afford another setback. With that in mind, do not be surprised if an uneventful contest ends in a low-scoring draw.
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Millwall vs. Blackburn (Saturday, 3.00pm)
Millwall square off against Blackburn Rovers on Saturday afternoon having started the new Championship campaign with a 1-1 draw at Queens Park Rangers.
While Rovers posted an impressive 2-1 win over Swansea City, the midweek exit to Morecambe in the EFL Cup has halted any momentum generated from their opening-day success.
We say: Millwall 2-1 Blackburn Rovers
Having gotten three points on the board last week, Blackburn will feel like they can play with a certain level of freedom. However, with Rovers still looking for a replacement for Armstrong, we fancy Millwall to edge this contest by the odd goal in three.
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Nott'm Forest vs. Bournemouth (Saturday, 3.00pm)
Nottingham Forest head into their Championship encounter with Bournemouth looking to respond to their last-gasp defeat at Coventry City last weekend.
Meanwhile, the visitors make the trip to the City Ground having posted a 2-2 draw against recently-relegated West Bromwich Albion on Friday.
We say: Nottingham Forest 1-2 Bournemouth
While Forest have the quality in their ranks to trouble their higher-quality opponents, the lack of rest could prove pivotal. With that in mind, we see the visitors outlasting Forest, eventually coming on strong during the second half to claim all three points.
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Reading vs. Preston (Saturday, 3.00pm)
Off to a sluggish start in league and cup, troubled Reading will seek to steady the ship when they host Preston North End at the Select Car Leasing Stadium on Saturday.
While the visitors were also beaten on the opening day of the Championship, they bounced back to progress in the EFL Cup during the week, but the Royals crashed out; losing 3-0 to Swansea.
We say: Reading 2-2 Preston North End
Even if expectations are realistic at both clubs, neither will want to continue a winless start to the league season much longer, but they may have to do just that, as the spoils are set to be shared on Saturday.
Reading's defensive deficiencies can be exposed again, while Preston seem unsure of their best XI under new manager McAvoy and are unlikely to shut out the home side for 90 minutes. Therefore, a tightly contested score draw is on the cards.
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West Brom vs. Luton (Saturday, 3.00pm)
Following their opening-day draw, West Bromwich Albion will seek a first success of the Championship season when they host Luton Town on Saturday.
While Valerien Ismael's side were held by Bournemouth last week, the Hatters travel to The Hawthorns having followed a fine league win with a humbling EFL Cup exit in midweek.
We say: West Bromwich Albion 2-1 Luton Town
Goals could be on the cards at the Hawthorns, as Luton have had a prolific pre-season and netted three on the opening day, while West Brom are now led by a notoriously attack-minded manager and have a number of weapons at their disposal - if not one star striker to finish everything off.
For that reason, the scoreline may remain close - but expect Albion to dictate the play and come out on top for a fifth straight time against the Hatters.
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Swansea vs. Sheff Utd (Saturday, 8.00pm)
Swansea City and Sheffield United will be looking to bounce back from opening game defeats in the Championship when they meet at the newly-named Swansea.com Stadium on Saturday.
The Swans went down 2-1 to Blackburn Rovers, while United lost 1-0 against Birmingham City on their return to the second tier.
We say: Swansea City 2-1 Sheffield United
Martin and Jokanovic could do with getting off the mark with their first league wins in charge of Swansea and United respectively, but at least one of them will be disappointed.
Swansea were let down by some sloppy moments against Blackburn but looked impressive against Reading, so we are backing the Swans to pick up all three points on home soil.