Scottish midfielder John Fleck is available again after missing Saturday's 1-0 win at Brighton due to suspension.
But Wilder could decide to stick with the same starting XI that triumphed on the south coast as the Blades look to continue their impressive Premier League form.
Watford midfielder Abdoulaye Doucoure will be suspended for the trip to Bramall Lane after he received his fifth yellow card of the Premier League season on Sunday.
Roberto Pereyra returned from injury to come off the bench in the 2-0 win over Manchester United while Adam Masina was an unused substitute after a recent problem.
Jose Holebas (ankle) remains sidelined along with long-term absentees Tom Cleverley (heel), Danny Welbeck (hamstring), Sebastian Prodl and Daryl Janmaat (both knee), while new signing Joao Pedro is ineligible to make his debut until January.
Sheffield United provisional squad: Henderson, Egan, O'Connell, Basham, Baldock, Norwood, Stevens, Lundstram, Morrison, Fleck, McGoldrick, Mousset, Robinson, Freeman, McBurnie, Moore, Sharp, Jagielka, Besic.
Watford provisional squad: Foster, Mariappa, Cathcart, Kiko, Kabasele, Hughes, Capoue, Deulofeu, Deeney, Sarr, Gomes, Dawson, Masina, Foulquier, Chalobah, Pereyra, Quina, Gray, Success.