Lorenzo Insigne has been drafted into the Napoli starting lineup against Siena away from home in Serie A this afternoon.
The Italian forward will partner Edinson Cavani in attack, while Hugo Campagnaro has replaced the suspended Paolo Cannavaro in defence.
Gokhan Inler's suspension and injury to Blerim Dzemaili mean that Marco Donadel starts for the Partenopei in midfield.
The game is Giuseppe Iachini's first game in charge of Siena after he replaced the sacked Serse Cosmi on Sunday.
Siena: Pegolo; Dellafiore, Contini, Felipe; Valiani, Bolzoni, D'Agostino, Rodriguez, Del Grosso; Rosina, Calaio
Napoli: De Sanctis; Campagnaro, Gamberini, Britos; Maggio, Behrami, Donadel, Hamsik, Zuniga; Insigne, Cavani