Southampton manager Ronald Koeman has predicted that his side will experience more problems against FC Midtjylland than they did against previous opponents Vitesse.
The Saints beat Vitesse 5-0 on aggregate to reach the Europa League playoffs, but Koeman has insisted that the Danish outfit shouldn't be taken lightly ahead of Thursday's first leg at St Mary's.
The 52-year-old told reporters: "They have played Champions League qualification games.
"I have mentioned already the draw is more difficult than Vitesse because they are more physical and don't play so open as a Dutch team does. That makes it difficult."
The winner of the two-legged tie will reach the group stages of the competition for the first time.