Southampton host Queens Park Rangers on Saturday afternoon as they look to move clear of the Premier League relegation zone.
The Saints are currently three points ahead of 18th place, and victory against the league's bottom club could see them move as high as 13th position.
Manager Mauricio Pochettino could replace Luke Shaw with Danny Fox, while Gaston Ramirez could return to the starting lineup.
Queens Park Rangers travel to St Mary's without a league win since January 2.
The Hoops are currently seven points adrift at the bottom of the Premier League table, and manager Harry Redknapp will be aware that his side desperately need three points against the Saints.
Redknapp may hand a start to Jermaine Jenas, while Loic Remy could return to the team after a spell out with a groin injury.
Recent form
Southampton: DDLDWL
Queens Park Rangers: DLDDLL
Possible starting lineups
Southampton: Boruc; Clyne, Yoshida ,Hooiveld, Shaw; Schneiderlin, Ramirez, Cork, Lallana; Lambert, Rodriguez
Queens Park Rangers: Julio Cesar; Traore, Samba, Hill; Bosingwa; Taarabt, Jenas, Townsend, M'bia, Mackie; Remy
Sports Mole says: 2-1