Tottenham Hotspur will be hoping to derail Manchester City's quadruple dream when they welcome Champions League football to their state-of-the-art new stadium for the first time on Tuesday.
The Premier League rivals have been drawn together in the quarter-finals of the Champions League, with Spurs bidding to make it into the last four for the first time.
Mauricio Pochettino's side have the benefit of a weekend off before the match due to the FA Cup, giving them extra time to heal up any injury concerns and ensure everyone is fit and firing for the mouth-watering contest.
Here, Sports Mole rounds up Tottenham's latest injury and suspension news ahead of the first leg.
TOTTENHAM HOTSPUR'S INJURY LIST
Status: Out
Type of injury: Hip
Possible return date: Unknown
A return date has not yet been set for Eric Dier, who has missed the last two games with a hip injury he sustained on international duty with England.
Status: Major doubt
Type of injury: Hamstring
Possible return date: April 9 (vs. Man City)
Serge Aurier also picked up an injury during the international break, lasting just 30 minutes of Ivory Coast's win over Rwanda. The exact severity of his hamstring injury has not yet been revealed, but he is considered a major doubt for Tuesday's match.
Fernando Llorente
Status: Slight doubt
Type of injury: Concussion
Possible return date: April 9 (vs. Manchester City)
Fernando Llorente missed the win over Crystal Palace due to concussion, but he is expected to have recovered fully in time to be in contention for a place in the squad on Tuesday.
Erik Lamela
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
Erik Lamela's last appearance for Spurs came in their last Champions League outing, but he will not play any part in the first leg of this tie due to a hamstring injury.
TOTTENHAM HOTSPUR'S SUSPENSION LIST
Spurs have no players suspended for this match, but Toby Alderweireld, Son Heung-min and Lamela are all one booking away from missing the second leg.