Tottenham Hotspur square off against Skendija 79 on Thursday night as they look to move closer to the Europa League group stages.
Spurs earned their place in the third qualifying round of the competition with a hard-fought victory over Bulgarian outfit Lokomotiv Plovdiv last week.
Although Jose Mourinho watched his side follow up that win with the second-half demolition of Southampton at the weekend, the Portuguese has several important decisions to make regarding his team selection.
Here, Sports Mole predicts how Spurs could line up for their upcoming encounter against the North Macedonian outfit.
Out: Japhet Tanganga (thigh), Gareth Bale (knee)
> Click here for Spurs' latest injury and suspension news ahead of this match
Although Mourinho has revealed that Dele Alli will feature in the travelling group, the playmaker is unlikely to earn a place in the starting lineup.
However, Mourinho is still expected to make numerous changes to his midfield, with Moussa Sissoko, Giovani Lo Celso and Steven Bergwijn all in line to return to the side.
Having only featured among the substitutes at the weekend, Toby Alderweireld is likely to replace either Eric Dier or Davinson Sanchez in defence.
Sergio Reguilon could make his debut for the North Londoners at some stage in the match, providing that he is registered to feature at this stage of the competition.
Gareth Bale, who has joined Reguilon in leaving Real Madrid for Spurs, is due to spend the next few weeks on the sidelines with a knee injury.
Japhet Tanganga also remains unavailable as he continues his recovery from a thigh problem.