Spurs somehow chucked away a three-goal lead with eight minutes to go to draw 3-3 with their London rivals, putting a bit of a blemish on their start to the campaign.
Austrian side LASK enter this opening Group J clash in good form, meanwhile, having won six of their opening nine matches in 2020-21.
Whether it was complacency or, as Jose Mourinho saw it, a case of one of those things, Tottenham's late collapse against West Ham will take a long time to fully get over.
For the best part of an hour Tottenham were at their brilliant best, with Harry Kane assisting one and scoring two as he showed yet again why he is one of the world's best players.
A point is all Mourinho's men have to show for it, though, giving them a rather mixed return of eight points from their first five Premier League games.
Throw a 6-1 triumph away at Manchester United into the mix, however, plus a quarter-final spot in the EFL Cup, and it is easy to see why many are getting excited.
The aim for Mourinho this season is ultimately to win a trophy, and in the Europa League he has a realistic shot of achieving that.
Spurs suffered a surprise last-32 defeat at the hands of Gent last time around, but they have successfully navigated the group stage in their last four attempts.
That is expected to be the case this time around, having been placed in a group that contains LASK, Ludogorets Razgrad and Royal Antwerp - hardly the biggest of hitters.
Mourinho will be hoping for the safest passage possible through to the knockout stages, while at the same time attempting to juggle the onslaught of domestic fixtures.
With trips to Burnley and Antwerp to come in the next week, closely followed by the visit of Brighton & Hove Albion, rotation is going to be key for the North London outfit.
That is something opponents LASK will be looking to take full advantage of, with the Austrian side themselves having aspirations of making it to at least the last 32.
The Black-Whites boast good Europa League credentials, too, finishing top of a group containing Sporting Lisbon, PSV Eindhoven and Rosenborg last season.
However, they went on to suffer a 7-1 aggregate defeat to Manchester United in the last 16 - their only previous meeting with an English club.
Tottenham have a little more experience of facing Austrian sides, meanwhile, having defeated SV Stockerau twice and FK Austria Wien once in their previous four such encounters.
Another win for Spurs will go a long way to putting the West Ham result behind them, although as ever with the Lilywhites you can never be certain of what is around the corner.
Tottenham Hotspur form (all competitions): WDWWWD
LASK Linz form (all competitions): DWWWLW
Gareth Bale was brought on as a second-half substitute against West Ham for his second debut and may be handed a full start here, fitness depending.
However, fellow Welshman Joe Rodon joined on domestic deadline day last week but was not registered in time to be eligible for the Europa League group phase.
As for the visitors, they eased to a 3-0 domestic cup win over Worgl at the weekend and will field their strongest available XI on Thursday.
Marko Raguz has scored five goals in six appearances this season, three of those coming in the qualifying phase of the Europa League as LASK saw off DAC Dunajksa Streda and Sporting Lisbon.
Tottenham Hotspur possible starting lineup:
Hart; Doherty, Sanchez, Alderweireld, Davies; Winks, Lo Celso, Alli; Lucas, Vinicius, Bale
LASK Linz possible starting lineup:
Lawal; Ramsebner, Wiesinger, Filipovic; Ranftl, Holland, Michorl, Renner; Gruber, Raguz, Balic
We say: Tottenham Hotspur 2-1 LASK Linz
LASK beat Sporting Lisbon in the final qualifying round and have won four of their last five matches in all competitions, so they cannot be written off.
Even accounting for the mass changes Mourinho is likely to make, however, Tottenham boast enough squad depth to kick off their Group J campaign with all three points.