Tottenham boss Nuno Espirito Santo wants his side to "go beyond our limits" as they aim to get back to the top table of English football.
Nuno, who left Wolves at the end of last season, has replaced Jose Mourinho in north London and has been handed the tough task of rebuilding Spurs.
It is two years since they were in the Champions League final, but they have since finished sixth and seventh in the Premier League and will compete in the much-maligned Europa Conference League this season.
With Manchester City, Chelsea and Manchester United all investing heavily this summer, and Liverpool also expected to improve from last season, a crack at the top four seems optimistic.
Kane's future will be decided one way or the other after Sunday's game, but Nuno is not prepared to discuss hypothetical situations.
Asked what life after Kane could look like, he replied: "You are asking things based on ifs and what eventually could happen. I cannot answer to that.
"I can answer based on reality and reality is: today, all the players that are here are with us. What can happen we don't know and I don't waste too much time thinking about this, I'm sorry."
Nuno said he will decide whether Kane will be involved after Saturday's training session.
He added: "All the decisions are not only based on fitness. It's based on many, many aspects that we have to consider.
"Football players are not only professional, they are people that deal with many situations.
"All of us, we have our own lives, and when we make decisions, I try to get as much info as I can so my decision is the best for the team. But many aspects we have to consider."
