League One leaders Bristol City avoided a shock in their match against League Two outfit AFC Wimbledon, with Aaron Wilbraham grabbing a brace in the final 20 minutes to secure their passage into the next round.
City were forced to wait until the 73rd minute to break the deadlock against a stubborn Wimbledon side, with Wilbraham eventually firing his side into the lead from close range.
The striker doubled his side's lead and his personal tally for the night just four minutes later to put the game beyond the visitors, finding the net from the edge of the box for his 11th goal of the season.
George Francomb did pull a goal back for Wimbledon with six minutes remaining, but ultimately it was not enough to see the League Two side force penalties.
Tranmere came from behind to reach the Northern area semi-final, eventually running out 2-1 winners over Bury at Gigg Lane.
The hosts opened the scoring 10 minutes before the break courtesy of a Nathan Cameron strike, but Max Power and Danny Johnson scored within two minutes of each other at the end of the half to give Tranmere the lead the interval.
That was how it stayed for the remainder of the match as the hosts failed to draw back level in the second half.
Gillingham also recovered from a one-goal deficit to progress at Crawley Town's expense, despite having to play the final half-hour with just 10 men.
Gillingham's task got even harder shortly after the hour mark when Joe Martin was shown a red card for pushing McLeod in the face, but they levelled things up just minutes later as Jermaine McGlashan fired home.
Leyton Orient were the most comfortable winners of the night, easing to a 2-0 victory over Northampton Town
Orient took a deserved lead shortly before the half-hour mark as Jay Simpson raced onto a through-ball and slotted his effort coolly past the keeper.
Results in full: Bristol City 2-1 AFC Wimbledon, Bury 1-2 Tranmere Rovers, Crawley Town 1-2 Gillingham, Leyton Orient 2-0 Northampton Town