Wigan Warriors centre Iain Thornley has been sidelined for the rest of the season with a serious knee injury.
The 22-year-old suffered the problem during a training session earlier this week.
Thornley, who could be missing for up to eight months, only recently returned to action after recovering from a chest injury.
"I'm devastated for Iain, he has worked incredibly hard this season to come back from an injury that looked to have finished his season," Warriors coach Shaun Wane told the club's official website.
"I couldn't have asked for any more from him, he is a great professional and deserves better luck than this."
Wigan continue their Super League campaign on Friday when they entertain Leeds Rhinos.