Max Malins has withdrawn from the England squad due to injury ahead of Saturday's clash against Canada at Twickenham.
The Rugby Football Union said that Saracens back Malins suffered a shoulder ligament injury during England's 43-29 victory over the United States last weekend.
Malins will see a specialist later this week for further assessment, with England head coach Eddie Jones deciding not to call up a replacement.
Malins lined up on the wing for England's summer series opener before going off.
England ran in seven tries against the United States, including a double for Bath's Joe Cokanasiga.
