Scotland have made five changes to their starting lineup for this weekend's Calcutta Cup clash against England.

Vern Cotter's men head to Twickenham without a win to their name in this year's Six Nations, with a surprise 22-19 defeat at home to Italy last time out compounding their misery.

Jim Hamilton, Finn Russell, Matt Scott, Dougie Fife and David Denton have all been brought into the side - the latter of that quintet being the only player yet to have featured in the tournament.

Denton will replace Johnnie Beattie for Saturday evening's match, while Sean Lamont, Alex Dunbar and Peter Horne also drop out.

Scotland team to face England: Stuart Hogg, Dougie Fife, Mark Bennett, Matt Scott, Tommy Seymour, Finn Russell, Greig Laidlaw, Alasdair Dickinson, Ross Ford, Euan Murray, Jim Hamilton, Jonny Gray, Robert Harley, Blair Cowan, David Denton

Replacements: Fraser Brown, Ryan Grant, Geoff Cross, Tim Swinson, Johnnie Beattie, Adam Ashe, Sam Hidalgo-Clyne, Greig Tonks