Ireland Under-20s coach Mike Ruddock believes that Wales can overcome England when the pair meet at the Millennium Stadium on March 16.
Ruddock, who coached Wales to Grand Slam success in 2005, has admitted, however, that Stuart Lancaster's side have been impressive in the Six Nations.
"As good as England are at the moment the real test for them will be going down to Cardiff to try and get a result," he told BBC Sport.
"I think Stuart Lancaster's done a fantastic job and there are some good coaches around him. Having said that Wales always pick their game up against English teams and particularly in Cardiff."
Wales currently sit second in the Six Nations table.