Peyton Hillis limped off the field during his Tampa Bay Buccaneers debut with a knee injury.
The running back sustained a knock to his left knee during the third quarter of the NFC South side's 44-16 loss to the Baltimore Ravens.
The 27-year-old had four carries for the team prior to his exit from the game, rushing for 13 yards.
Hillis joined the Buccaneers last month, having spent the 2012 season with the Kansas City Chiefs.