Salernitana vs. Sassuolo (Saturday, 2.00pm)
While the visitors have won three games on the spin to move inside the top half, their hosts are 10 points adrift of safety after a seven-match winless streak.
We say: Salernitana 1-3 Sassuolo
Though they have tightened up at the back under new management - an expected mauling by Inter aside - Salernitana are the league's lowest scorers and have found the net just 10 times on home soil this term.
Therefore, their lack of attacking threat should allow Sassuolo to get forward at will; unleashing their fantastic foursome to secure a fourth win on the spin.
Spezia vs. Cagliari (Saturday, 2.00pm)
The pair convene in Liguria, with the visitors trailing their hosts by just a point in the standings following an upturn in fortunes during February.
We say: Spezia 1-1 Cagliari
Having shipped 50 league goals already, Spezia are not the most defensively sound side, but their opponents have often failed to deliver in the final third.
Neither team is likely to keep a clean sheet, so these two relegation rivals will share the spoils with a score draw.
Sampdoria vs. Juventus (Saturday, 5.00pm)
The Bianconeri edged out Spezia last weekend to extend their unbeaten run to a 14th Serie A match and are in striking distance of top spot with 10 games left to play. Samp, meanwhile, merely aim to maintain their top-flight status.
We say: Sampdoria 1-2 Juventus
With rock-bottom Salernitana next to play in Serie A, Juve's unbeaten run should continue until next month's Derby d'Italia at least, as they can come away from Marassi with all three points.
While rarely an attractive watch, Allegri's men are becoming well versed in the practice of seeing out narrow victories, while their opponents have previously won just four times from 14 attempts on home turf.
AC Milan vs. Empoli (Saturday, 7.45pm)
While the Rossoneri returned to the top of the pile following last week's crucial win over Scudetto rivals Napoli, they have sometimes struggled against the league's minnows so will be keen to take three points against a team yet to win in 2022.
We say: AC Milan 2-0 Empoli
Only 18th-placed Venezia have conceded more shots on target than Empoli's total of 162 in Serie A this season, so an opportunity surely presents itself for Milan to stretch their lead in the standings.
The hosts' scoring rate may have dipped in recent weeks, but Leao and Giroud have been in impressive form, with 'King Zlatan' also bringing his charismatic presence to bear on the bench. Therefore, Empoli's winless run will roll on.