Arsenal manager Mikel Arteta may have to contend without as many as six defenders and one midfielder for Wednesday's Champions League battle with Monaco at the Emirates Stadium.
The Gunners lost Oleksandr Zinchenko to an unknown injury before the 1-1 Premier League draw with Fulham on Sunday, a tie that Riccardo Calafiori, Gabriel Magalhaes, Ben White and Takehiro Tomiyasu also missed.
Thomas Partey and Jurrien Timber started at right and left-back respectively on Sunday, but the pair were also not able to train with the team on Tuesday for unexplained reasons and are major doubts for the midweek battle too.
Arteta refused to give too much away in his pre-game press conference, but his hand will likely be forced at the back, where one of two academy graduates in Josh Robinson or Josh Nichols could deputise at right-back.
Kieran Tierney has been restricted to a watching brief so far this season but should now be a genuine contender to start on the left-hand side, while Jakub Kiwior and William Saliba are shoo-ins in the central areas.
Regardless of Partey's fitness, Arteta should give rise to a midfield alteration, as Mikel Merino could bump Jorginho down to the bench as Declan Rice and Martin Odegaard reprise their roles.
Leandro Trossard failed to make a major impact as a starter once again in the draw with Fulham, so Gabriel Martinelli should be promoted for this one, even if he was needlessly offside for Bukayo Saka's disallowed winner at Craven Cottage.
Arsenal possible starting lineup:
Raya; Robinson, Saliba, Kiwior, Tierney; Odegaard, Rice, Merino; Saka, Havertz, Martinelli
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