Arsenal can all but seal their progress in the Champions League on Tuesday if they beat Marseille at home in Group F.
The Gunners currently top the standings ahead of Napoli on goal difference following their impressive 1-0 win at Borussia Dortmund two weeks ago.
Meanwhile, Marseille's chance of reaching the last 16 were ended last time out as they went down 3-2 at Napoli.
Arsenal earned a 2-1 win when the teams met at the Stade Velodrome on September 18.
Theo Walcott is likely to start on the bench for the hosts after returning from injury over the weekend, while Rod Fanni and Andre Ayew remain sidelined for the visitors.
Recent form
Arsenal: WLWWLW
Marseille: LLDLWW
Possible starting lineups
Arsenal: Szczesny; Sagna, Koscielny, Mertesacker, Gibbs; Arteta, Ramsey, Wilshere, Ozil, Cazorla; Giroud
Marseille: Mandanda; Abdallah, N'Koulou, Diawara, Mendy; Thauvin, Romao, Cheyrou, Payet; Valbuena, Gignac
Sports Mole says: 2-0