Valencia manager Gary Neville has named a much-changed starting XI for the first leg of Los Che's Europa League last-16 tie against fellow Spanish outfit Athletic Bilbao.
Only two players - Shkodran Mustafi and Javi Fuego - keep their place from the La Liga defeat to Atletico Madrid on Sunday.
The home side, meanwhile, come into this match on a three-game winning streak and they show only one change from the 2-0 triumph at Sporting Gijon.
It comes in midfield, with Ander Iturraspe taking Mikel San Jose's place.
Athletic Bilbao: Herrerin; De Marcos, Etxeita, Laporte, Balenziaga; Iturraspe, Benat, Susaeta, Raul Garcia, Muniain; Aduriz
Subs: Iraizoz, Boveda, Inigo Lekue, Elustondo, Eraso, Rico, Merino
Valencia: Ryan, Mustafi, Gaya, Barragan, Abdennour, Parejo, Danilo, Javi Fuego, Negredo, Piatti, Rodrigo
Subs: Domenech, Cancelo, Vezo, Feghouli, Gomes, Alcacer, Mina