Segunda Division B outfit Sant Andreu play host to La Liga table-toppers Atletico Madrid in the fourth round of the Copa del Rey on Saturday.
The Catalan side have only won one of their last five games, leaving them 16th after 16 games in the Spanish third tier.
Meanwhile, Diego Simeone's men - unbeaten in six games - have only dropped four points this season and are level with Barcelona at the top of the league.
The Argentine will likely rest players for the trip to Narcis Sala, especially with Raul Garcia, Arda Turan, Filipe, Koke and Gabi being one yellow card from suspensions.
Ibon Gutierrez and Francis are a caution away from incurring bans for the home side, although that is unlikely to deter Patxi Salinas from selecting them in his lineup.
The second leg takes place at the Vicente Calderon on December 18.
Recent form
Sant Andreu: DLWDL
Atletico: WWWDWW
Possible starting lineups
Sant Andreu: Morales, Canelada, Arnau, Navarro, Azparren, Gutierrez, Vitoria, Alcover, Jimenez, Francis, Araujo
Atletico: Aranzubia, Alderweireld, Miranda, Insua, Juanfran, Guilavogui, Torres, Tiago, Rodriguez, Costa, Adrian
Sports Mole says: 0-5