There are only two points between the two sides in the table ahead of this weekend's contest, with Barca currently occupying third position, while Sevilla are fourth, comfortably clear of fifth-placed Real Sociedad.
Sevilla have been in impressive form during the 2020-21 La Liga campaign, winning 15, drawing three and losing five of their 23 matches to collect 48 points, which has left them in fourth position in the table.
Julen Lopetegui's side are just two points behind third-placed Barca and just four points off second-placed Real Madrid, with games in hand over both sides, while they are seven points clear of fifth-placed Real Sociedad, meaning that a top-four position is fairly secure at this stage of the season.
Sevilla now face back-to-back games with Barca as they will also take on Ronald Koeman's side in the second leg of their Copa del Rey semi-final next week, holding a 2-0 advantage from the first leg at Estadio Ramon.
Domestically, Lopetegui's side continue to impress, but they have work to do in the Champions League, having suffered a 3-2 home defeat to Borussia Dortmund in the first leg of their last-16 clash on February 17.
Like Sevilla, the Catalan giants are facing Champions League elimination, having lost 4-1 at home to Paris Saint-Germain in the first leg of their last-16 tie, while, as mentioned, they have work to do in the second leg of their Copa del Rey semi-final, which should be a fascinating contest at Camp Nou.
There is no getting away from the fact that Barca have had problems this season, both on the field and behind the scenes, but they are unbeaten in the league since the start of December and have won eight of their last nine in Spain's top flight to close the gap on the teams above them.
Koeman's side are currently third, two points behind second-placed Real Madrid, while they are only five points off leaders Atletico, suggesting that a title challenge is not impossible at this stage.
Barca only have the fourth best away record in La Liga this season, though, suffering three defeats, and they were held to a goalless draw in the corresponding match during the 2019-20 campaign.
Sevilla La Liga form: WWWWWW
Sevilla form (all competitions): WWWWLW
Barcelona La Liga form: WWWWDW
Barcelona form (all competitions): WLWLDW
Sevilla will again be without the services of key attacker Lucas Ocampos, who has scored seven times this season, due to an ankle problem, while Marcus Acuna is also out with a hamstring issue.
As for Barca, Sergi Roberto, Ansu Fati, Ronald Araujo and Philippe Coutinho remain unavailable for selection, but the Catalan giants did not pick up any fresh injury or suspension issues against Elche.
Sevilla possible starting lineup:
Bounou; Navas, Kounde, Carlos, Rekik; Jordan, Fernando, Rakitic; Suso, En-Nesyri, Munir
Barcelona possible starting lineup:
Ter Stegen; Dest, Pique, Lenglet, Alba; De Jong, Busquets, Pedri; Griezmann, Messi, Dembele
We say: Sevilla 1-1 Barcelona
The last two league matches between these two teams have finished level, and we are finding it difficult to separate them once again. Sevilla were excellent against Barca in the Copa del Rey earlier this month, and we are backing Lopetegui's side to secure a point on Saturday afternoon.