Hoffenheim vs. Union Berlin (Saturday, 2.30pm)
Union Berlin head to Hoffenheim on Saturday on the cusp of qualifying for the Champions League for the first time in the club's history.
The hosts, meanwhile, may require four points from their final two matches to avoid finishing in the bottom three.
We say: Hoffenheim 2-2 Union Berlin
This is a hugely important match for both teams at either end of the table, with a victory potentially enough for either side to achieve their respective ambitions.
However, avoiding defeat would not be the end of the world as it would ensure that their destiny remains in their own hands heading into the final match of the season, or potentially even better than that depending on results elsewhere. As such, we can envisage a share of the spoils after an entertaining affair.
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Hertha Berlin vs. VfL Bochum (Saturday, 2.30pm)
Hertha Berlin must defeat VfL Bochum at the Olympiastadion on Saturday, otherwise they will be relegated from the Bundesliga for the first time in a decade.
Bochum, meanwhile, head into the encounter six points clear of their forthcoming opponents, but they are only one position above the relegation zone.
We say: Hertha Berlin 1-2 VfL Bochum
Hertha's race appears to be run as far as their time in the Bundesliga goes, and we can envisage Bochum massively increasing their own chances of survival while condemning their opponents to relegation with a victory on Saturday.
Having struggled to avoid defeat on the road for long periods of this season, Letsch's side have only lost one of their last four away games, so it would be surprising if they did not depart the capital with at least a point to their name.
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Schalke vs. Frankfurt (Saturday, 2.30pm)
Fighting for their Bundesliga lives, Schalke 04 occupy the dreaded relegation playoff spot ahead of Saturday's pivotal showdown with Eintracht Frankfurt at Veltins-Arena.
The hosts suffered a 6-0 mauling at the hands of Bayern Munich last weekend, while the visitors ended a 10-game winless run in the league with a 3-0 victory over Mainz 05.
We say: Schalke 04 2-2 Eintracht Frankfurt
Given Eintracht Frankfurt have failed to record an away league victory since November, we expect a desperate Schalke outfit to get something from Saturday's clash, although the hosts will likely struggle to claim all three points.
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Werder Bremen vs. FC Koln (Saturday, 2.30pm)
Free-falling Werder Bremen are still in danger of relegation as they prepare to host FC Koln in the penultimate round of Bundesliga matches on Saturday.
While the River Islanders have lost four of their last five games, the Billy Goats have won three of their previous four, setting up an intriguing battle at Weserstadion.
We say: Werder Bremen 1-2 FC Koln
While in-form FC Koln have won four of their last six matches to steer clear of relegation trouble, Werder Bremen have suffered seven defeats in 10 outings to remain in danger.
With that in mind, we expect the Billy Goats to notch a fourth successive away victory on Saturday, inflicting a fifth straight home defeat on the River Islanders in the process.
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Bayern vs. RB Leipzig (Saturday, 5.30pm)
As the Bundesliga title race reaches its climax, Bayern Munich would put themselves within a whisker of their 11th straight championship triumph by beating RB Leipzig on Saturday evening.
Die Roten are in control of their own destiny thanks to a one-point lead over closest rivals Borussia Dortmund, and victory for Thomas Tuchel's team at the Allianz Arena would mean defeat for Dortmund on Sunday would put the Meisterchale back in Bavarian hands.
We say: Bayern Munich 3-1 RB Leipzig
All but ending the closest Bundesliga title race in 13 years, Bayern are set to sweep aside Leipzig; leaving the pressure piled on Dortmund. At their fluent best against Schalke, the champions may be stepping up in class this week, but such are their attacking riches they can tame the Red Bulls once again.
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