Bayern Munich coach Pep Guardiola has opted to rest Arjen Robben and Mario Mandzukic for the trip to Bayer Leverkusen, with both players named on the bench.
Thomas Muller moves forward to play as the lone striker, while Xherdan Shaqiri comes into the XI in place of Robben.
For Leverkusen, Son Heung-Min is dropped to the bench, while Gonzalo Castro is deemed fit enough for a place among the substitutes.
Leverkusen: Leno; Donati, Spahic, Toprak, Boenisch; Bender, Reinartz, Rolfes; Sam, Can, Kiessling
Bayern: Neuer; Rafinha, Boateng, Dante, Alaba; Lahm; Shaqiri, Schweinsteiger, Kroos, Ribery; Muller