Charlton Athletic are heading for a fourth straight defeat, courtesy of Federico Macheda's first-half goal.
The home side had a penalty shout turned down early on as Astrit Ajdarevic played in Reza Ghoochannejhad, who went down under Will Packwood's challenge, though the referee waved away Charlton calls.
The deadlock was broken courtesy of Macheda's goal, with the striker heading home a Emyr Huws cross with 22 minutes on the clock.
Brum nearly doubled their lead shortly after, with Chris Burke through on goal only for Yohann Thuram-Ulien to rush out and prevent the Scottish winger with his feet.
Relegation-threatened Chalrton nearly pulled level through Jordan Cousins who found himself one-on-one with the keeper, though Darren Randolph came out on top to save the attempt.
Randolph was called into action once more shortly after, this time from a Johnnie Jackson strike which the visiting stopper had to push away.