Liverpool will not be welcoming Thiago Alcantara back to the fold for Sunday's crunch match with Premier League title rivals Chelsea at Stamford Bridge.
The Spaniard has recovered from COVID-19 but missed the defeat at Leicester City due to muscle soreness, with Takumi Minamino out for the same reason.
Thiago and Minamino have now been ruled out of this contest as well, while Adrian, Divock Origi, Nat Phillips and Harvey Elliott also remain injured.
Andy Robertson will serve the third and final game of his domestic suspension this weekend, meaning Kostas Tsimikas can look forward to another start in a likely unchanged backline.
With Thiago not fit enough to take part this weekend, Alex Oxlade-Chamberlain could keep his place in the XI as Fabinho and Jordan Henderson also hold their spots.
Mohamed Salah and Sadio Mane are available for one more game before the Africa Cup of Nations comes calling, with the duo expected to start in the final third once more despite their misfiring tendencies at the King Power.
Roberto Firmino will hope to rejoin Salah and Mane to form the famed front three in the capital, but Jurgen Klopp may elect to keep the faith in Diogo Jota once again.
Liverpool possible starting lineup: Alisson; Alexander-Arnold, Matip, Van Dijk, Tsimikas; Henderson, Fabinho, Oxlade-Chamberlain; Salah, Jota, Mane
> Click here to see how Chelsea could line up for Sunday's game