Juan Luis Anangono missed a 92nd-minute penalty in Chicago Fire's 1-1 draw with New England Revolution as both sides finished with 10 men.
Quincy Amarikwa fired the hosts ahead on 16 minutes, latching onto a Harry Shipp pass before slotting past goalkeeper Bobby Shuttleworth.
The advantage lasted just 15 minutes, though, as Lee Nguyen kept his cool from 12 yards to equalise from the penalty spot on the half-hour mark.
Amarikwa received his marching orders with 17 minutes of normal time remaining as the Revolution looked to capitalise on their numerical advantage.
Jay Heaps' men soon found themselves down to 10 after Kevin Alston conceded a penalty before being dismissed with a straight red card.
However, Anangono saw the resulting spot kick saved by Shutteworth as the Revolution held on for a point.