Fiorentina winger Juan Cuadrado is expected to start against Roma, despite being heavily linked with Chelsea earlier this week.
Chelsea boss Jose Mourinho has attempted to dismiss reports regarding the 26-year-old, but it remains to be seen whether the Colombian will be plying his trade in Italy for the remainder of the season.
The Viola have failed to keep a clean sheet in their last seven games, but 15 goals have been netted over the same period and Vincenzo Montella's team have a chance of moving into third place with a win.
Khouma Babacar took his tally for the season to six when netting a last-minute winner at Chievo last weekend, but he could remain on the bench after Mario Gomez scored a brace in the Coppa Italia in midweek.
Roma make the trip to Florence in second place in the Serie A standings but despite being unbeaten in their last six league games, they have drawn four times to see them fall further behind leaders Juventus.
The Giallorossi are also finding it tough in front of goal, with the club only scoring more than twice in a game on one occasion since November 9, which isn't enough for a team chasing the league title.
Defender Ashley Cole could find himself drafted into the team for just his 10th league appearance in place of Jose Holebas.
Club legend Francesco Totti may also start after playing just 66 minutes of the extra-time triumph over Empoli in the Coppa Italia.
Fiorentina:
Form in Serie A: DWDLWW
Form in all competitions: WLDWWW
Possible starting lineup: Tatarusanu, Rodriguez, Pasqual, Basanta, Tomovic, Joaquin, Fernandez, Borja Valero, Cuadrado, Badelj, Gomez
Roma:
Form in [League/Comp]: DWDWDD
Form in all competitions: WDWDDW
Possible starting lineup: De Sanctis, Cole, Yanga-Mbiwa, Astori, Pjanic, Strootman, Paredes, Florenzi, Totti, Destro, Iturbe
Sports Mole says: 1-2