Genoa vs. Fiorentina (Thursday, 5.30pm)
After picking up just one point from five games, Serie A strugglers Genoa will try to stop the rot against in-form Fiorentina when the teams meet on Thursday.
The Viola head for Marassi on the back of five straight wins, racking up no fewer than 19 goals in the process, while the hosts have called upon an ageing star to help revive their ailing fortunes.
We say: Genoa 1-2 Fiorentina
Genoa boss Alberto Gilardino is set to suffer more misery against one of his former clubs, as injuries have bitten his squad hard.
With Fiorentina in red-hot form, the hosts will have their hands full at the back - and they are missing key men throughout the final third.
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Como vs. Lazio (Thursday, 7.45pm)
After posting back-to-back wins over the past week, Lazio will visit Como on Thursday evening, aiming to end October on a high.
The Biancocelesti have won four of five games this month - in Europe and Serie A - while their promoted hosts have endured a downturn.
We say: Como 1-2 Lazio
While Como have competed well in the top flight, Lazio are heading for Lombardy in peak form and boasting a goal-hungry attack.
The Biancocelesti can therefore end their hosts' unbeaten run at Stadio Sinigaglia, keeping themselves in the pack behind Serie A leaders Napoli.
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Roma vs. Torino (Thursday, 7.45pm)
Having decided to stand by their head coach for now, Roma are set to tackle Serie A rivals Torino on Thursday night, at Stadio Olimpico.
Ivan Juric comes face to face with his old team after surviving crisis talks at the capital club, desperate to bounce back from a humbling defeat.
We say: Roma 2-2 Torino
Torino have both scored and conceded 10 goals away from home this season, averaging two per game, and that trend could continue in the capital.
As a disjointed Roma side are still struggling for form amid confusion off the pitch, the hosts may fail to win once again.