Zenit St Petersburg forward Hulk is rested for their Champions League tie with Gent as the Russian side look to become only the sixth team to win all six group games in Champions League history.
Andre Villas-Boas is also without midfielder Axel Witsel, who misses out through suspension.
Gent defender Rami Gershon has not recovered from a knee problem and will not feature.
Danish striker Nicklas Pedersen also misses out, but Lasse Nielsen has recovered from a hamstring strain and starts for Hein Vanhaezebrouck's side.
Gent: Sels; Rafinha, Mitrovic, Nielsen; Asare, Renato Neto, Kums, Foket, Milicevic; Depoitre, Simon
Subs: Vandenbussche, Vitas, Coulibaly, Poletanović, Saief, Van der Bruggen, Dejaegere
Zenit St Petersburg: Lodygin; Anyukov, Criscito, Lombaerts, Luís Neto, Garay; Ryazantsev, Yusupov, Javi García; Danny, Dzyuba
Subs: Kerzhakov, Ivanov, Zuev, Shatov, Troyanov, Bogaev, Dolgov
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