January signings Ezequiel Schelotto and Zdravko Kuzmanovic make their debuts for Inter Milan in the Serie A clash against Siena this afternoon.
Fredy Guarin also starts for Inter, despite an suffering an injury scare in training.
However, Diego Milito, Esteban Cambiasso and Walter Samuel are all missing for Inter.
Siena also hand debuts to their new signings Emeghara and Alessandro Rosina, while Nicola Pozzi is out of the game with an injury.
Siena: Pegolo; Belmonte, Paci, Felipe; Angelo, Vergassola, Della Rocca, Rubin; Rosina, Sestu; Emeghara
Inter: Handanovic; Ranocchia, Chivu, Juan Jesus; Schelotto, Kuzmanovic, Zanetti, Nagatomo; Guarin; Cassano, Palacio