Nemanja Vidic and Xherdan Shaqiri have been dropped by Inter Milan for their Serie A match against Genoa.
The pair both started in Inter's 2-1 loss to Juventus last week, but are replaced by Yuto Nagatomo and Hernanes for tonight's match.
Genoa can move up to fifth in the Serie A table with a win, and will rely on top scorer Iago Falque to lead the line.
Armando Izzo and Maxime Lestienne miss out for the hosts and are replaced by Tino Costa and Sebastian De Maio
Genoa: Perin; Roncaglia, Burdisso, De Maio; Rincon, Tino Costa, Kucka, Edenilson; Bertolacci, Pavoletti, Iago Falque
Inter Milan: Handanovic; D'Ambrosio, Ranocchia, Juan Jesus, Nagatomo; Brozovic, Medel, Kovacic; Hernanes; Palacio, Icardi