However, Isloch know that victory over their in-form opponents will move them level on points with the third-place outfit.
Failing to make the most of games against teams lower down the standings has resulted in Isloch dropping down to sixth place, eight points adrift of leaders BATE Borisov.
Given the competitive nature of the division, they are also just four points above 12th position, highlighting that they need to bounce back from two defeats in three games as soon as possible.
Succumbing to Dinamo Minsk represented a significant blow to Vitaly Zhukovsky's side, with last week's then-lowly opponents having gone into the game on the back of two setbacks in a row.
With two players, Momo Yansane and Dmitri Komarovskiy, having contributed all but four of their goals this season, Zhukovsky will feel that it is time that they are provided with more assistance in the final third.
Nevertheless, Energetik boss Vladimir Belyavskiy finds himself in a similar situation with Jasurbek Yaxshiboev having contributed half of his team's tally for the campaign.
Three of his six strikes have come from the penalty spot, while the fact that two doubles have been recorded during that run suggests that more help is required.
That said, Belvavskiy will find it difficult to have many complaints with a team which have registered three wins in a row after a run of the same amount of defeats.
The Students now find themselves as challengers for a first-ever top-flight crown, having never finished higher than 12th place in their history.
While Belvavskiy will reiterate that it is still early days, another three points at the weekend will leave Energetik just one point behind pacesetters BATE.
Isloch form: LWWLWL
Energetik-BGU form: LLLWWW
Head To Head
Despite sitting higher in the league standings, Energetik have not recorded a single competitive victory over Isloch in their last five games.
Most notably, Saturday's hosts have recorded three successive victories by one-goal margins, a run which began just 12 months ago.
The other two fixtures, staged in 2015, ended in draws.
We say: Isloch 1-1 Energetik-BGU
While neither side have recorded a single draw this season, we feel that could change this weekend. Isloch will be motivated to remain in the top half of the table, and that desire could give them an edge against opponents who are under pressure to last the pace in the top three.