Atalanta vs. Spezia (Saturday, 2.00pm)
Following a sticky spell in October, Atalanta BC will seek to continue this month's winning ways when Serie A resumes, as they welcome Spezia to Bergamo on Saturday.
While the fourth-placed hosts edged out Cagliari just before the international break, their Ligurian visitors also claimed maximum points - with just their third win of a difficult second season among the elite.
We say: Atalanta BC 3-1 Spezia
Though they have not yet torn teams apart as they did so often at their peak last season, Atalanta have managed to accumulate points steadily and are always capable of scoring from a range of sources.
As ever, the Nerazzurri's wide men could play a crucial role in exploiting their opponents' greatest flaws, and Spezia look vulnerable to their combination of pace and power.
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Lazio vs. Juventus (Saturday, 5.00pm)
Two of Serie A's big guns convene on Saturday evening, as Lazio welcome Juventus to Stadio Olimpico, with both sides sitting outside the top four.
While the fifth-placed hosts have been undermined by inconsistency, Juve trail them by three points and three places in the standings after a miserable first third of the domestic campaign.
We say: Lazio 1-1 Juventus
Even if Juve's need for the points is relatively greater - given both teams' pre-season expectations - it will be a tough task for Allegri's men to return from Rome with maximum points on Saturday night.
Lazio's home record matches up favourably with most on the continent since the turn of the year, and if their star forwards can overcome injury to play a role in proceedings, the hosts can pick up a point to stay three ahead of the Bianconeri.
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Fiorentina vs. AC Milan (Saturday, 7.45pm)
Sitting seven points clear of the chasing pack upon Serie A's resumption, joint-leaders AC Milan continue their Scudetto quest with a trip to Tuscany, where they meet Fiorentina on Saturday evening.
Level on points with Napoli at the summit of the standings, the Rossoneri have won 10 of their 12 league games following a Milan Derby draw, while their inconsistent hosts have both won and lost half of their fixtures.
We say: Fiorentina 2-2 AC Milan
Injury concerns at the back may undermine their cause, but Fiorentina play an enterprising brand of football when the opportunity arises, and can take confidence from a positive home record which features two recent wins by a 6-0 aggregate scoreline.
Milan, of course, are of a different calibre than Cagliari and Spezia, but the Rossoneri may be held again this weekend due to their hosts' impressive attacking options, which have seen them average two goals per game on Florentine soil.