Roma coach Zdenek Zeman has decided to deploy Daniele De Rossi in central midfield against Lazio at the Stadio Olimpico this afternoon.
Zeman has not used the central midfielder in his usual role so far this season, but he replaces Panagiotis Tachtsidis with the Italy international.
Francesco Totti, Erik Lamela and Pablo Daniel Osvaldo are the three attackers for the Lupi, while Miroslav Klose will spearhead Lazio's attack.
The German forward will be supported by Hernanes, Stefano Mauri and Antonio Candreva.
Lazio: Marchetti; Konko, Biava, Dias, Lulic; Ledesma; Candreva, Gonzalez, Hernanes, Mauri; Klose
Roma: Goicoechea; Piris, Marquinhos, Burdisso, Balzaretti; Bradley, De Rossi, Florenzi; Lamela, Osvaldo, Totti