SM
| First Half starts. | ||
| 3' | Fouled by Robert Andrich - Bayer 04 Leverkusen | |
| 3' | Nabil Fekir - Real Betis - won a free kick in attack. | |
| 4' | Fouled by Robert Andrich - Bayer 04 Leverkusen | |
| 4' | Nabil Fekir - Real Betis - won a free kick in defence. | |
| 5' | New attacking attempt. Borja Iglesias - Real Betis - shot with right foot from outside the box is saved in the top centre of the goal. Assist - William Carvalho. | |
| 7' | New attacking attempt. Paulinho - Bayer 04 Leverkusen - shot with right foot from outside the box is saved by goalkeeper in the centre of the goal. Assist - Kerem Demirbay with a through ball. | |
| 8' | New attacking attempt. Florian Wirtz - Bayer 04 Leverkusen - shot with right foot from outside the box is saved by goalkeeper in the centre of the goal. Assist - Jeremie Frimpong. | |
| 8' | Fouled by Kerem Demirbay - Bayer 04 Leverkusen | |
| 8' | Nabil Fekir - Real Betis - won a free kick in attack. | |
| 9' | Fouled by Amine Adli - Bayer 04 Leverkusen | |
| 9' | Nabil Fekir - Real Betis - won a free kick in attack. | |
| 9' | Fouled by Amine Adli - Bayer 04 Leverkusen | |
| 9' | Marc Bartra - Real Betis - won a free kick in defence. | |
| 9' | Amine Adli - Bayer 04 Leverkusen - receive yellow card for a foul. | |
| 10' | Shot blocked. Aitor Ruibal - Real Betis - header inside of six yard box - left side is blocked. | |
| 10' | Corner - Real Betis. Conceded by Jeremie Frimpong. | |
| 13' | Missed chance. Kerem Demirbay - Bayer 04 Leverkusen - shot with left foot from outside the box missed. Assist - Edmond Tapsoba. | |
| 13' | New attacking attempt. Moussa Diaby - Bayer 04 Leverkusen - shot with left foot from the left side of the box is saved in the left corner. Assist - Florian Wirtz. | |
| 17' | Shot blocked. Kerem Demirbay - Bayer 04 Leverkusen - shot with left foot from outside the box is blocked. Assist - Jeremie Frimpong. | |
| 17' | Corner - Bayer 04 Leverkusen. Conceded by Víctor Ruiz. | |
| 18' | Missed chance. Aitor Ruibal - Real Betis - shot with right foot from outside the box is high and wide to the right. | |
| 20' | Shot blocked. Amine Adli - Bayer 04 Leverkusen - shot with left foot from the right side of the box is blocked. Assist - Robert Andrich. | |
| 21' | Fouled by Amine Adli - Bayer 04 Leverkusen | |
| 21' | William Carvalho - Real Betis - won a free kick in defence. | |
| 23' | Missed chance. Kerem Demirbay - Bayer 04 Leverkusen - shot with right foot from the right side of the box is high and wide to the right. Assist - Amine Adli. | |
| 24' | Offside - Bayer 04 Leverkusen. Moussa Diaby with a pass, however Jeremie Frimpong is in offside. | |
| 25' | VAR Decision: No Goal Bayer 04 Leverkusen 0-0 Real Betis. | |
| 28' | Offside - Bayer 04 Leverkusen. Moussa Diaby with a pass, however Jeremie Frimpong is in offside. | |
| 31' | Fouled by Jeremie Frimpong - Bayer 04 Leverkusen | |
| 31' | Juan Miranda - Real Betis - won a free kick on the left wing. | |
| 33' | Corner - Bayer 04 Leverkusen. Conceded by Víctor Ruiz. | |
| 34' | Amine Adli - Bayer 04 Leverkusen - won a free kick in defence. | |
| 34' | Fouled by Aitor Ruibal - Real Betis | |
| 35' | New attacking attempt. Nabil Fekir - Real Betis - shot with left foot from outside the box is saved by goalkeeper in the centre of the goal. Assist - Borja Iglesias. | |
| 35' | Corner - Real Betis. Conceded by Lukás Hrádecky. | |
| 35' | New attacking attempt. Guido Rodríguez - Real Betis - shot with the head from the centre of the box is saved by goalkeeper in the centre of the goal. Assist - Joaquín with a cross. | |
| 36' | Offside - Bayer 04 Leverkusen. Moussa Diaby with a pass, however Amine Adli is in offside. | |
| 37' | New attacking attempt. Aitor Ruibal - Real Betis - shot with right foot from outside the box is saved in the left corner. | |
| 37' | Offside - Real Betis. Guido Rodríguez with a pass, however Borja Iglesias is in offside. | |
| 38' | Missed chance. Moussa Diaby - Bayer 04 Leverkusen - shot with left foot from outside the box missed to the left. Assist - Florian Wirtz. | |
| 39' | Borja Iglesias - Real Betis - won a free kick in defence. | |
| 39' | Fouled by Edmond Tapsoba - Bayer 04 Leverkusen | |
| 40' | Fouled by Moussa Diaby - Bayer 04 Leverkusen | |
| 40' | Guido Rodríguez - Real Betis - won a free kick in defence. | |
| 41' | Corner - Real Betis. Conceded by Jonathan Tah. | |
| 42' | Goal! Bayer 04 Leverkusen 1, Real Betis 0. Moussa Diaby - Bayer 04 Leverkusen - shot with right foot from the right side of the box to the right corner. Assist - Florian Wirtz. | |
| 44' | Fouled by Robert Andrich - Bayer 04 Leverkusen | |
| 44' | Nabil Fekir - Real Betis - won a free kick in attack. | |
| 44' | Robert Andrich - Bayer 04 Leverkusen - receive yellow card for a foul. | |
| 45+1' | Offside - Bayer 04 Leverkusen. Edmond Tapsoba with a pass, however Paulinho is in offside. | |
| 45+2' | First Half ended - Bayer 04 Leverkusen 1, Real Betis 0. | |
| 45' | Second Half starts Bayer 04 Leverkusen 1, Real Betis 0. | |
| 45' | Substitution - Real Betis. Sergio Canales for William Carvalho. | |
| 45' | Substitution - Real Betis. Álex Moreno for Juan Miranda. | |
| 46' | Fouled by Borja Iglesias - Real Betis | |
| 46' | Jonathan Tah - Bayer 04 Leverkusen - won a free kick in defence. | |
| 50' | New attacking attempt. Kerem Demirbay - Bayer 04 Leverkusen - shot with left foot from outside the box is saved in the left corner. Assist - Florian Wirtz. | |
| 51' | Fouled by Kerem Demirbay - Bayer 04 Leverkusen | |
| 51' | Nabil Fekir - Real Betis - won a free kick in defence. | |
| 52' | Shot blocked. Florian Wirtz - Bayer 04 Leverkusen - shot with right foot from the centre of the box is blocked. Assist - Piero Hincapié. | |
| 52' | Goal! Bayer 04 Leverkusen 2, Real Betis 0. Moussa Diaby - Bayer 04 Leverkusen - shot with left foot from outside the box to the top right corner. | |
| 54' | Corner - Real Betis. Conceded by Jeremie Frimpong. | |
| 54' | Shot blocked. Borja Iglesias - Real Betis - shot with right foot inside of six yard box - left side is blocked. Assist - Nabil Fekir with a cross. | |
| 54' | Corner - Real Betis. Conceded by Edmond Tapsoba. | |
| 56' | New attacking attempt. Amine Adli - Bayer 04 Leverkusen - shot with left foot from outside the box is saved in the left corner. | |
| 57' | Shot blocked. Sergio Canales - Real Betis - shot with left foot from outside the box is blocked. Assist - Nabil Fekir. | |
| 59' | Substitution - Real Betis. Rodrigo Sánchez for Aitor Ruibal. | |
| 60' | Missed chance. Robert Andrich - Bayer 04 Leverkusen - shot with right foot from outside the box is close, but missed. Assist - Moussa Diaby. | |
| 62' | Missed chance. Nabil Fekir - Real Betis - shot with right foot from outside the box missed to the left. | |
| 63' | Fouled by Kerem Demirbay - Bayer 04 Leverkusen | |
| 63' | Joaquín - Real Betis - won a free kick in defence. | |
| 65' | Florian Wirtz - Bayer 04 Leverkusen - won a free kick in attack. | |
| 65' | Fouled by Guido Rodríguez - Real Betis | |
| 66' | Fouled by Amine Adli - Bayer 04 Leverkusen | |
| 66' | Guido Rodríguez - Real Betis - won a free kick in attack. | |
| 67' | Nabil Fekir - Real Betis - hits the bar with a shot with left foot from outside the box from a free kick. | |
| 68' | Missed chance. Amine Adli - Bayer 04 Leverkusen - shot with left foot from the right side of the box missed to the left. Assist - Florian Wirtz. | |
| 69' | Substitution - Bayer 04 Leverkusen. Exequiel Palacios for Paulinho. | |
| 70' | Shot blocked. Kerem Demirbay - Bayer 04 Leverkusen - shot with right foot from the left side of the box is blocked. | |
| 71' | Shot blocked. Moussa Diaby - Bayer 04 Leverkusen - shot with left foot from the left side of the box is blocked. Assist - Florian Wirtz. | |
| 71' | Missed chance. Florian Wirtz - Bayer 04 Leverkusen - shot with left foot from the centre of the box missed to the left. | |
| 71' | Substitution - Real Betis. Willian José for Borja Iglesias. | |
| 75' | Shot blocked. Sergio Canales - Real Betis - shot with left foot from outside the box is blocked. Assist - Willian José. | |
| 75' | Corner - Real Betis. Conceded by Robert Andrich. | |
| 76' | Missed chance. Willian José - Real Betis - shot with right foot from the centre of the box missed. Assist - Joaquín with a cross. | |
| 77' | Substitution - Bayer 04 Leverkusen. Nadiem Amiri for Amine Adli. | |
| 78' | Substitution - Bayer 04 Leverkusen. Daley Sinkgraven for Piero Hincapié. | |
| 78' | Fouled by Jeremie Frimpong - Bayer 04 Leverkusen | |
| 78' | Álex Moreno - Real Betis - won a free kick on the left wing. | |
| 79' | Substitution - Real Betis. Juanmi for Joaquín. | |
| 80' | New attacking attempt. Kerem Demirbay - Bayer 04 Leverkusen - shot with left foot from outside the box is saved in the left corner. Assist - Exequiel Palacios. | |
| 80' | Florian Wirtz - Bayer 04 Leverkusen - won a free kick in defence. | |
| 80' | Fouled by Víctor Ruiz - Real Betis | |
| 83' | Missed chance. Robert Andrich - Bayer 04 Leverkusen - shot with right foot from outside the box is high and wide to the right. Assist - Kerem Demirbay. | |
| 85' | Shot blocked. Rodrigo Sánchez - Real Betis - shot with left foot from the right side of the box is blocked. Assist - Héctor Bellerín. | |
| 85' | Corner - Real Betis. Conceded by Daley Sinkgraven. | |
| 85' | New attacking attempt. Marc Bartra - Real Betis - shot with the head from the centre of the box is saved in the top left corner. Assist - Rodrigo Sánchez with a cross. | |
| 85' | Corner - Real Betis. Conceded by Lukás Hrádecky. | |
| 86' | Goal! Bayer 04 Leverkusen 3, Real Betis 0. Florian Wirtz - Bayer 04 Leverkusen - shot with right foot from the centre of the box to the top left corner. Assist - Moussa Diaby with a through ball. | |
| 88' | Substitution - Bayer 04 Leverkusen. Odilon Kossounou for Florian Wirtz. | |
| 88' | Substitution - Bayer 04 Leverkusen. Panagiotis Retsos for Jeremie Frimpong. | |
| 89' | Shot blocked. Sergio Canales - Real Betis - shot with left foot from outside the box is blocked. Assist - Guido Rodríguez. | |
| 90' | Goal! Bayer 04 Leverkusen 4, Real Betis 0. Nadiem Amiri - Bayer 04 Leverkusen - shot with right foot from few metres to the centre of the goal. Assist - Moussa Diaby. | |
| 90+2' | Fouled by Kerem Demirbay - Bayer 04 Leverkusen | |
| 90+2' | Nabil Fekir - Real Betis - won a free kick on the right wing. | |
| 90+3' | Nabil Fekir - Real Betis - receive red card for violent conduct. | |
| 90+3' | Kerem Demirbay - Bayer 04 Leverkusen - receive red card for violent conduct. | |
| 90+5' | Second Half ended - Bayer 04 Leverkusen 4, Real Betis 0. | |
| Thats all. Game finished - Bayer 04 Leverkusen 4, Real Betis 0. |
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