Wayne Rooney and Robin van Persie have been omitted from the Manchester United squad for tomorrow's Champions League encounter with Galatasaray in Istanbul.
With the Red Devils having already qualified for the final 16 of the competition with two group matches to spare, manager Sir Alex Ferguson has opted to rest his striking duo.
The experienced quarter of Rio Ferdinand, Patrice Evra, Ryan Giggs and Paul Scholes have also been left behind for the trip.
Spanish goalkeeper David de Gea will also not travel following an operation to remove his wisdom teeth.
A host of youngsters have been included in the 21-man squad, including Nick Powell, Josh King and Larnell Cole.
Man United squad:
Sam Johnstone, Anders Lindegaard; Rafael, Alexander Buttner, Phil Jones, Tom Thorpe, Marnick Vermijl, Scott Wootton; Michael Carrick, Davide Petrucci, Larnell Cole, Tom Cleverley, Darren Fletcher, Anderson, Nick Powell, Ashley Young, Ryan Tunnicliffe; Javier Hernandez, Joshua King, Danny Welbeck, Federico Macheda