Marouane Fellaini and Marcus Rashford have both been selected in Manchester United's starting lineup for the Champions League fixture with Sevilla.
Fellaini has not started a fixture for United since November, but gets an opportunity to impress at Old Trafford in place of Scott McTominay.
On Saturday, Rashford marked his return to the side with two goals against Liverpool, and Jose Mourinho has decided to reward the England international with a second outing in three days.
Paul Pogba returns to the squad after a minor injury, but the club's record signing must do with a place among the replacements.
As for Sevilla, manager Vincenzo Montella has made just one alteration to the team which started the goalless draw in Spain last month.
Simon Kjaer returns to the first XI, while Jesus Navas is not involved on his first return to Manchester since leaving United's neighbours City.
Manchester United: De Gea; Valencia, Bailly, Smalling, Young; Matic, Fellaini; Lingard, Sanchez, Rashford; Lukaku
Subs: Romero, Darmian, Lindelof, McTominay, Mata, Pogba, Martial
Sevilla: Rico; Mercado, Kjaer, Lenglet, Escudero; N'Zonzi, Banega, Sarabia, Vazquez, Correa; Muriel
Subs: Ben Yedder, Geis, Soria, Pizarro, Pareja, Nolito, Lopes
Follow the match in the North-West of England with Sports Mole's live commentary.