Louis van Gaal has made four changes to the Manchester United starting XI for the trip to FC Midtjylland tonight, including a first start for youngster Donald Love.
The 21-year-old replaces Matteo Darmian in the back four after the Italian dislocated his shoulder in the 2-1 defeat at Sunderland on Saturday.
Cameron Borthwick-Jackson also missed the trip to Denmark and is replaced by Paddy McNair, while Ander Herrera and Memphis Depay come in for the injured Marouane Fellaini and Wayne Rooney, pushing Anthony Martial into a centre-forward role.
There is also young blood on the United bench with Regan Poole, Joe Riley and James Weir hoping to play some part in the Europa League last-32 tie.
The hosts have not played a league match since December 4 owing to the lengthy Danish winter break and name a strong side, but are without the services of veteran midfielder Jakob Poulsen, who is suspended for the game.
FC Midtjylland: Andersen; Romer, Kian, Bodurov, Novak; Kadlec, Sparv, Olsson, Hassan, Sisto; Pusic
Manchester United: De Gea, Love, Smalling, McNair, Blind, Herrera, Carrick, Lingard, Mata, Memphis, Martial
Subs: Romero, Poole, Riley, Pereira, Schneiderlin, Weir, Keane
Follow live coverage of the match from Denmark with Sports Mole's live text commentary here.