Wayne Rooney will start at centre-forward for Manchester United in Thursday's Europa League clash with Fenerbahce, while Zlatan Ibrahimovic has dropped to the bench.
Rooney has shaken off a thigh problem to replace out-of-form Ibrahimovic at the tip of the Man United attack, while Frenchman Anthony Martial has also returned from injury to start in a wide position.
Elsewhere, Morgan Schneiderlin is drafted into central midfield alongside Ander Herrera, while Henrikh Mkhitaryan is back in the Man United squad for the first time since the start of September.
As for Fenerbahce, former Man United striker Robin van Persie is only named on the bench.
Emmanuel Emenike impressed after coming off the bench in the reverse match last month, but the centre-forward's position goes to Moussa Sow, while fit-again Jeremain Lens, formerly of Sunderland, also returns to the home side's XI.
Martin Skrtel and Simon Kjaer keep their positions in central defence for Fenerbahce.
Fenerbahce: Volkan; Sener, Kjaer, Skrtel, Ali; Mehmet, Josef, Alper; Lens, Sow, Sen
Subs: Fabiano, Van Persie, Koybasi, Emenike, Neustadter, Salih Ucan, Stoch
Manchester United: De Gea; Darmian, Blind, Rojo, Shaw; Schneiderlin, Herrera; Rashford, Pogba, Martial; Rooney
Subs: Romero, Jones, Fellaini, Mata, Mkhitaryan, Young, Ibrahimovic
Follow Sports Mole's minute-by-minute live commentary of the action here.
